Compile Data Set for Download or QSAR
Found 169 of ic50 data for polymerid = 8451
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM16314(2-{[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]-...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM50241828(CHEMBL4089817)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:Inhibition of recombinant human AKR1B10 using pyridine-3-aldehyde as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ89S7PubMed
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM50241817(CHEMBL4081954)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Inhibition of recombinant human AKR1B10 using pyridine-3-aldehyde as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ89S7PubMed
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM50442489(CHEMBL2440417)copy SMILEScopy InChI
Affinity DataIC50: 4.70nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged AKR1B10 expressed in Escherichia coli by fluorescence assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3MX4PubMed
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM50442489(CHEMBL2440417)copy SMILEScopy InChI
Affinity DataIC50: 4.70nMAssay Description:Inhibition of AKR1B10 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ89S7PubMed
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM50321717(7-hydroxy-2-(4-methoxyphenylimino)-N-(pyridin-2-yl...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of reductase activity of N-terminal 6His-tagged AKR1B10 expressed in Escherichia coli BL21(DE3) assessed as inhibition of NADPH linked pyr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35TTHPubMed
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM50241818(CHEMBL4060049)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human AKR1B10 using pyridine-3-aldehyde as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ89S7PubMed
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM50321717(7-hydroxy-2-(4-methoxyphenylimino)-N-(pyridin-2-yl...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged AKR1B10 expressed in Escherichia coli by fluorescence assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3MX4PubMed
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM50362835(CHEMBL1940400)copy SMILEScopy InChI
Affinity DataIC50: 6.20nMAssay Description:Inhibition of human recombinant N-terminus His6-tagged AKR1B10 expressed in Escherichia coli BL21 DE3 assessed as pyridine-3-aldehyde reduction by sp...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4RDBPubMed
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM50241816(CHEMBL4098452)copy SMILEScopy InChI
Affinity DataIC50: 6.40nMAssay Description:Inhibition of recombinant human AKR1B10 using pyridine-3-aldehyde as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ89S7PubMed
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM50442501(CHEMBL2440422)copy SMILEScopy InChI
Affinity DataIC50: 6.80nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged AKR1B10 expressed in Escherichia coli by fluorescence assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3MX4PubMed
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM50241822(CHEMBL4062779)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant human AKR1B10 using pyridine-3-aldehyde as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ89S7PubMed
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM50241826(CHEMBL4089816)copy SMILEScopy InChI
Affinity DataIC50: 7.5nMAssay Description:Inhibition of recombinant human AKR1B10 using pyridine-3-aldehyde as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ89S7PubMed
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM50442504(CHEMBL2440423)copy SMILEScopy InChI
Affinity DataIC50: 7.60nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged AKR1B10 expressed in Escherichia coli by fluorescence assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3MX4PubMed
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM50241821(CHEMBL4068704)copy SMILEScopy InChI
Affinity DataIC50: 7.80nMAssay Description:Inhibition of recombinant human AKR1B10 using pyridine-3-aldehyde as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ89S7PubMed
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM50241827(CHEMBL4071421)copy SMILEScopy InChI
Affinity DataIC50: 8.30nMAssay Description:Inhibition of recombinant human AKR1B10 using pyridine-3-aldehyde as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ89S7PubMed
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM50442499(CHEMBL2440424)copy SMILEScopy InChI
Affinity DataIC50: 8.60nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged AKR1B10 expressed in Escherichia coli by fluorescence assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3MX4PubMed
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM50442495(CHEMBL2440416)copy SMILEScopy InChI
Affinity DataIC50: 8.80nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged AKR1B10 expressed in Escherichia coli by fluorescence assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3MX4PubMed
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM50362841(CHEMBL1940399)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant N-terminus His6-tagged AKR1B10 expressed in Escherichia coli BL21 DE3 assessed as pyridine-3-aldehyde reduction by sp...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4RDBPubMed
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM50442506(CHEMBL2440411)copy SMILEScopy InChI
Affinity DataIC50: 9.70nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged AKR1B10 expressed in Escherichia coli by fluorescence assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3MX4PubMed
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM50241823(CHEMBL4084456)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human AKR1B10 using pyridine-3-aldehyde as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ89S7PubMed
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM50241829(CHEMBL4071420)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human AKR1B10 using pyridine-3-aldehyde as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ89S7PubMed
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM50442498(CHEMBL2440414)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged AKR1B10 expressed in Escherichia coli by fluorescence assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3MX4PubMed
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM50442502(CHEMBL2440415)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged AKR1B10 expressed in Escherichia coli by fluorescence assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3MX4PubMed
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM50442494(CHEMBL2440428)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged AKR1B10 expressed in Escherichia coli by fluorescence assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3MX4PubMed
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM16314(2-{[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]-...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of retinaldehyde reductase activity of human AKR1B10More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM50362846(CHEMBL1940394)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant N-terminus His6-tagged AKR1B10 expressed in Escherichia coli BL21 DE3 assessed as pyridine-3-aldehyde reduction by sp...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4RDBPubMed
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM50442503(CHEMBL2440427)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged AKR1B10 expressed in Escherichia coli by fluorescence assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3MX4PubMed
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM50442505(CHEMBL2440426)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged AKR1B10 expressed in Escherichia coli by fluorescence assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3MX4PubMed
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM50362844(CHEMBL1940396)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant N-terminus His6-tagged AKR1B10 expressed in Escherichia coli BL21 DE3 assessed as pyridine-3-aldehyde reduction by sp...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4RDBPubMed
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM50362843(CHEMBL1940397)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant N-terminus His6-tagged AKR1B10 expressed in Escherichia coli BL21 DE3 assessed as pyridine-3-aldehyde reduction by sp...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4RDBPubMed
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM50442500(CHEMBL2440425)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged AKR1B10 expressed in Escherichia coli by fluorescence assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3MX4PubMed
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM50321718(2-(2,4-dimethoxyphenylimino)-7-hydroxy-N-(pyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of reductase activity of N-terminal 6His-tagged AKR1B10 expressed in Escherichia coli BL21(DE3) assessed as inhibition of NADPH linked pyr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35TTHPubMed
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM50362842(CHEMBL1940398)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant N-terminus His6-tagged AKR1B10 expressed in Escherichia coli BL21 DE3 assessed as pyridine-3-aldehyde reduction by sp...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4RDBPubMed
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM50442496(CHEMBL2440413)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged AKR1B10 expressed in Escherichia coli by fluorescence assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3MX4PubMed
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM50362845(CHEMBL1940395)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of human recombinant N-terminus His6-tagged AKR1B10 expressed in Escherichia coli BL21 DE3 assessed as pyridine-3-aldehyde reduction by sp...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4RDBPubMed
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM50442497(CHEMBL2440412)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged AKR1B10 expressed in Escherichia coli by fluorescence assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3MX4PubMed
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM50241830(CHEMBL3318218)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human AKR1B10 using pyridine-3-aldehyde as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ89S7PubMed
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM50362847(CHEMBL1940393)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant N-terminus His6-tagged AKR1B10 expressed in Escherichia coli BL21 DE3 assessed as pyridine-3-aldehyde reduction by sp...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4RDBPubMed
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM50321715(2-(2,5-dimethoxyphenylimino)-7-hydroxy-N-(pyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of reductase activity of N-terminal 6His-tagged AKR1B10 expressed in Escherichia coli BL21(DE3) assessed as inhibition of NADPH linked pyr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35TTHPubMed
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM50362840(CHEMBL1940401)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant N-terminus His6-tagged AKR1B10 expressed in Escherichia coli BL21 DE3 assessed as pyridine-3-aldehyde reduction by sp...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4RDBPubMed
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM50394657(CHEMBL270067)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of recombinant human intestinal N-terminal 6-His-tagged AKR1B10 expressed in Escherichia coli BL21 (DE3) pLysS cells using pyridine-3-alde...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ89S7PubMed
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM200221(2-(5-chloro-2-(((perbromophenyl)methyl)carbamoyl)p...)copy SMILEScopy InChI
Affinity DataIC50: 30nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM50049730(2-(5-(2-methyl-3-phenylallylidene)-4-oxo-2-thioxot...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of human Protein kinase C beta 2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46WHWPubMed
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM50321716(2-(3,4-dimethoxyphenylimino)-7-hydroxy-N-(6-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of reductase activity of N-terminal 6His-tagged AKR1B10 expressed in Escherichia coli BL21(DE3) assessed as inhibition of NADPH linked pyr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35TTHPubMed
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM50049730(2-(5-(2-methyl-3-phenylallylidene)-4-oxo-2-thioxot...)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Inhibition of Protein kinase C zetaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46WHWPubMed
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM16314(2-{[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]-...)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:Inhibition of reductase activity of N-terminal 6His-tagged AKR1B10 expressed in Escherichia coli BL21(DE3) assessed as inhibition of NADPH linked pyr...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM16314(2-{[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]-...)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:Inhibition of human N-terminal His-tagged AKR1B10 expressed in Escherichia coli BL21 using retinaldehyde as substrateMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM50059989((1E,4Z,6E)-5-Hydroxy-1,7-bis-(4-hydroxy-phenyl)-he...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of AKR1B10 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ89S7PubMed
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM50362851(CHEMBL1940390)copy SMILEScopy InChI
Affinity DataIC50: 69nMAssay Description:Inhibition of human recombinant N-terminus His6-tagged AKR1B10 expressed in Escherichia coli BL21 DE3 assessed as pyridine-3-aldehyde reduction by sp...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4RDBPubMed
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